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Welcome to Resolve Parkinson's

A new Paradigm for Parkinson's Syndrome

Resolve Parkinson's proposes a  new paradigm for Parkinson's Syndrome based on reclassifying all PD symptoms according to their underlying cause. This paradigm makes sense of non-motor symptoms and opens the way to disease-modifying therapies.

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The Redox Stress Test

A new test developed by Resolve Parkinson's shows that non-motor symptoms are related to oxidative stress.

Redox Stress Test graph data

Total symptom response to the Redox Stress Test:
Individual case response to the Redox Stress Test. Results for grouped motor and non-motor symptom scores over 6 weeks.

What is Resolve Parkinson's?
A non-profit organisation directed by an
international group of Parkinson's patients with expert knowledge and lived experience of Parkinson's. We are dedicated to developing disease-modifying therapies for Parkinson's.
 

What is our main line of research?
We focus on attenuating non-motor symptoms of PD, especially fatigue, constipation and urinary urgency. The Redox Stress Test developed by Resolve Parkinson's shows that these symptoms are caused by oxidative stress and mitochondrial dysfunction in the brain, the intestines and the urinary tract. Suppressing oxidative stress in these peripheral organs is a prerequisite to slowing or stopping PD progression. This research is led by Dr Albert Wright, Director of Research at Resolve Parkinson's.

How advanced is the research?

Technically, the research is very advanced. We use a natural product called sulforaphane to stimulate the body's own antioxidant defences. Sulforaphane neutralises oxidative stress and attenuates non-motor symptoms of PD in only 2-4 weeks. The Redox Stress Test developed by RP shows that many non-motor symptoms are caused by oxidative stress in the brain, the intestines and the urinary tract, whereas motor symptoms are not.

Pioneering patient-led researchto transform Parkinson’s

Senior Couple

What is RP's objective?
Our objective is to convince Public Health authorities that suppressing oxidative stress in the intestinal and urinary tracts is an essential step towards controlling or preventing PD. We also want to prove through further research and clinical trials that sulforaphane is safe and effective to control oxidative stress and make it available worldwide to People suffering from Parkinson's.
 

We need your help to Resolve Parkinson's
You can help Resolve Parkinson's in many ways. Taking part in and organising testing, advocacy, general organisation, fund raising, management, communications... 

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Together we can transform Parkinson's.

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Subscribing to our website is your first step to supporting the RP Team who are working tirelessly to bring you new information  to help transform your Parkinson's. Subscription is free and your email address will only be used to keep you informed of future events.


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