The Problem:

Research Targets Are Profit-Driven

About Us

We are people with Parkinson’s dedicated to elevating the voices of those with lived experience of Parkinson’s to inform the way Parkinson’s is understood, treated, and ultimately cured.

What We Offer

Resolve Parkinson’s offers opportunities for you to contribute to a changed future. You can help us transform the future of Parkinson’s.

Big Pharma's influence is stalling the search for a cure. The influence of profit-driven motives has skewed Parkinson's research priorities, leaving patients without the answers and innovations they desperately need. Decisions about how resources are allocated are controlled by pharmaceutical companies and academic institutions, prioritizing treatments that maximize financial returns rather than patient outcomes.

The Status Quo is a System Designed to Maintain Profits

Despite decades of research, we still don’t know what causes Parkinson’s, what drives its progression, or how to stop it. The most reliable treatment — medication developed 50 years ago — offers temporary symptom relief but ultimately fails as patients require higher doses over time, leading to debilitating side effects.

Newer drugs, such as dopamine agonists, aim to delay these challenges but often bring severe complications like hallucinations and compulsive behaviors. These side effects create a cycle of additional medications, each with its own risks, compounding patients’ suffering while enriching pharmaceutical companies. Promising natural remedies and lifestyle changes — like exercise and mindfulness — receive little research funding because they can’t be patented or monetized. The result is a system that prioritizes profits over potentially transformative solutions.

The Cost of Misaligned Incentives

Globally, 11 million people are diagnosed with Parkinson’s, and the number of patients over 65 is expected to double within the next decade. In the U.S. alone, the Parkinson’s drug market was valued at $97.59 billion in 2023 and is projected to grow to $171.46 billion by 2031. With such enormous financial stakes, there is little incentive to find a cure that would disrupt this lucrative market.

Steps Towards a Solution: Prioritizing Patient-Centered Research

We believe that by addressing these systemic flaws, we can drive the progress necessary to find a cure for Parkinson’s and improve the quality of life for millions worldwide. Learn more about our vision for the future and how we’ll get there.

The Problems We See

The System of Care is Poorly Designed

The current system to assist people with Parkinson’s appears to have evolved without rational planning. Systemic issues include lack of patient access to Parkinson’s specific care, ineffective drug therapies, and a poorly socialized standard of care in health settings. This has led many patients to try to manage their care on their own.

The Definition of Parkinson’s is Too Narrow

Parkinson’s is a multisystemic syndrome rather than solely a movement disorder limited to brain neurology. A focus on non-motor symptoms is critical to understanding how Parkinson’s evolves and how early intervention may slow or halt the disease.

Alternative Therapies are Excluded from Research

Led by desperation and ineffective drug therapies, patients with Parkinson’s have found relief through lifestyle changes and treatments that aren’t patentable or otherwise able to be monetized. These approaches have been eschewed by the mainstream medical community.

There is a Lack of Access to Quality Care

Most patients with Parkinson’s lack access to multidisciplinary teams of specialists including neurologists trained in Parkinson’s, movement disorder specialists, physical and occupational therapists, and mental health professionals. This team approach has proven to be the most effective model of care for Parkinson’s patients.

The Patient Voice is Being Ignored

Parkinson’s patients need to have a seat at the table throughout the clinical research process. Patient input into how resources are used is a critical missing element that will bring about change if broadly applied. Positioning the patient voice more powerfully will disrupt stagnation and drive change.

Researchers Ask the Wrong Questions

There is a dearth of creative thinking in the Parkinson’s field. Research priorities need to shift to include the investigation of a broader range of hypotheses concerning Parkinson’s origin and progression. Out-of-the-box thinking can spur innovation that may lead to a breakthrough towards better treatment and a cure.
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